If you read the ARS article @Ronin linked it says in there that these patches will likely not affect the average user since the average user either wouldn’t be using intensive applications (Specifically applications that have a very high volume of Kernal calls) or would just be gaming which apparently isn’t affected. It says that when the patch is pushed out to all, it will be opt-out for non-enterprise users.
One of the big places at least the Intel patch effects is running VMs so @adrock may well see some impact given the nature of your work, @n0tch too in the same regard and maybe @Jester dependant on the number of VMs you run. Even then, the worst prediction I’ve seen is cutting kernal calls from 6mil to 2.5/3mil which seems like it would hit industrial scale VMs (Amazon, Google, etc) far more than those who aren’t running VMs on such a massive scale.
The full scale and nature of the flaws aren’t even fully public yet, but the ARS article descibes the ‘Meltdown’ flaw in decent detail and highlights why that flaw is at present confined to Intel CPUs and some ARM chips but not AMD (at least not yet).